Molecular Biosciences (PhD/MPhil/MD)
PhD 3-4 years; MPhil 1-2 years; MD 2 years (Full-time) / PhD 5 years; MPhil 2-3 years; MD 3 years (Part-time) / n/a (Distance / E-Learning)
Molecular Biosciences focuses on the molecular mechanisms underpinning biological function. The Division has a broad strength that spans biochemistry, structural and synthetic biology, cell biology, molecular genetics and developmental biology. The groups within Molecular Biosciences focus on a variety of biological systems including Drosophila, yeast, Arabidopsis, tobacco, Dictyostelium, and mammalian cells, and have a growing strength in the use of post-genomic and systems approaches to solve biological problems.
Molecular Biosciences is an innovative, well funded and cohesive Division with excellent modern facilities for a broad range of techniques. It has close links with Chemistry in structural biology and with Physics in the development of advanced imaging technologies, and collaborates globally with academic and industrial partners. Research within Molecular Biosciences has a broad impact in areas including increasing our understanding of basic biological systems, improving diagnosis and therapy for human diseases and the development of novel commercialisable technologies.
The spectrum of research activities includes engineering protein structure and function, gene regulation, chromatin function, molecular genetics of development, cancer biology, and basic cell biological processes, such as cell division, cell death, cell signalling, motility and chemotaxis.
- Gene function and expression in Drosophila muscle and heart differentiation
- Regulation of gene expression in Drosophila spermatogenesis
- Regulation of mRNA translation in time and space in Drosophila development
- Molecular basis of sensory systems and extracellular signalling
- Genome-wide chromatin analysis to study gene regulation and DNA repair
- Control of GSK-3 mediated cell signalling and protein complexes Wnt signalling and breast cancer
- Control of Dictyostelium chemotaxis and morphogenesis
- Regulation of protein and lipid trafficking
- Pollen-pistil interactions and membrane trafficking in plant reproduction
- Molecular and cell biology of the plant cell cycle
- Metabolism and function of lipids in plants
- Omega-3 polyunsaturated fatty acids in health and disease
- Regulation of plant senescence and stress responses
- Systems biology and modelling approaches to understanding the integration of cell division in plant development
- Structure of membrane proteins using electron microscopy approaches
- Design of novel protein scaffolds and molecular switches
- Synthetic biology through a reprogrammed genetic code
- Novel molecular diagnostics using bioluminescent outputs in real-time
- Novel laser-scanning microscopy based on Coherent Antistokes Raman Scattering
- Novel optical biosensors
For details of ongoing projects and collaborations, please visit the web pages of individual Molecular Biosciences Division members.
Suitable for graduates in Biological and Related Sciences.
A 1st or Upper 2nd class UK honours degree or equivalent is usually required; MSc/MPhil for PhD Programme.
Applicants whose first language is not English will be required to pass either IELTS/TEOFL exams. Minimum requirements are normally IELTS band 6.5 or TOEFL 600 (250 for computer-based test).
Note: International students pursuing part-time programmes of study are not eligible for Tier 4 General Student) visas and must have alternative leave to remain in the UK if they intend to study at the University in person.
Applicants are asked to hand in a research proposal alongside their application. If you are applying for an advertised project, there is no requirement of submitting a research proposal, instead please submit a statement of support.
Students must submit evidence of funding wherever possible – especially when funded by external sponsors.
UK & EU Full Time for 2014/15 unless otherwise specified below
UK & EU Part Time for 2014/15 unless otherwise specified below
International Full Time for 2014/15 unless otherwise specified below
International Part Time for 2014/15 unless otherwise specified below
Next intake: The University has four entry points for research degrees; 1st October, 1st January, 1st April or 1st July
Name: Mrs Swapna Khandavalli
Telephone: +44 (0)29 2087 5243
Fax: +44 (0)29 2087 5211