Organic Synthesis (PhD/MPhil)
PhD 3-4 years; MPhil 1-2 years (full-time) / n/a (part-time) / n/a (distance / e-Learning)
The School of Chemistry has developed a particular strength in Organic Synthesis, with a research group dedicated to this exciting area of study. As part of the Chemistry (PhD/MPhil) programme, students can conduct their research within this group.
To offer knowledge and expertise for a career in the pharmaceuticals and fine chemical sectors, teaching, biomedical research fields, research and managerial roles in general manufacturing industry (eg. food, cosmetics, petrochemical etc).
- The School has undergone extensive restructuring in the last few years and occupies newly refurbished laboratories with excellent facilities for research and teaching.
- Organic Chemistry continues to attract an expanding team of researchers, as well as maintaining an extensive network of industrial contacts.
- Strong interdisciplinary collaborations support projects across traditional subject divisions; postgraduates interact across these groups.
- New facilities for synthetic and catalytic chemistry, including an advanced pressurereaction suite for catalyst development and investigation.
- Extensive international collaborations; a number of research programmes allow placements abroad, including in Europe and America.
The research carried out within the Organic Synthesis group is largely focused on the development of novel synthetic methods and applications of these in target synthesis, most often either natural products or biologically active compounds of pharmaceutical or agrochemical significance. In many cases, the inspiration for developing the new methodology arises from a consideration of the structural features of such targets.
Particular areas of current interest are in heterocyclic synthesis, both saturated and heteroaromatic. Driven by the demands of industry and environmental considerations, much of this effort is aimed at defining new methods for the highly efficient and catalytic generation of such compounds. This can involve new heterogeneous catalysts, reactions in flow systems and the application of novel rearrangement reactions or radical chemistry.
A particularly strong theme is the formation of such compounds by the electrophile-driven addition of nucleophiles to unsaturated carbon-carbon bonds. A long standing interest in pericyclic reactions continues in the areas of Diels-Alder chemistry, various sigmatropic rearrangements and electrocyclic reactions. Organocatalysis, an increasingly important area in view of the toxicity of many transition metals, is well represented within the group. Current target types include complex polycyclic peptides, alkaloids, steroids, terpene alkaloids and plant-derived oxygen heterocycles.
Suitable for graduates with a good honours degree or equivalent in chemistry or a related subject.
Entry to research degree courses in chemistry will be subject to the University requirements for English language. In addition, the university offers a range of pre-sessional courses for those without the required language qualifications; successful completion of any of these courses will allow you to proceed with your research degree in chemistry.
Note: International students pursuing part-time programmes of study are not eligible for Tier 4 General Student) visas and must have alternative leave to remain in the UK if they intend to study at the University in person.
Next intake: The University has four entry points for research degrees: 1 October, 1 January, 1 April, or 1 July
Name: Dr Ben Ward
Telephone: +44(0)29 2087 0302
Fax: +44(0)29 2087 4030